Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Determination of Chemical Constituents of the Marine Pulmonate Slug, Paraoncidium reevesii

Bian-Na Sun^1,2, He-Ding Shen¹ , Hong-Xi Wu^2,3, Li-Xiang Yao¹, Zhi-Qing Cheng¹, Ya Diao¹

¹Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306; ²Zhejiang Mariculture Research Institute; ³Zhejiang Key Lab of Exploitation and Preservation of Coastal Bio-Resource, Wenzhou 325005, China.

For correspondence:- He-Ding Shen Email: hdshen@shou.edu.cn Tel:+86 21 61900446

Received: 16 May 2014 Accepted: 29 October 2014 Published: 15 December 2014

Citation: Sun B, Shen H, Wu H, Yao L, Cheng Z, Diao Y. Determination of Chemical Constituents of the Marine Pulmonate Slug, Paraoncidium reevesii. Trop J Pharm Res 2014; 13(12):2071-2074 doi: 10.4314/tjpr.v13i12.18

© 2014 The authors.
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Abstract

Purpose: To isolate and identify the chemical components of Paraoncidium reevesii.

Methods: Silica gel column chromatography was used to isolate the components from petroleum ether and ethyl acetate fractions of the acetone extract, and the structures of the compounds were derived from ¹H-nuclear magnetic resonance (¹H-NMR), ¹³C-nuclear magnetic resonance (¹³C-NMR) and mass spectrometry (MS) analyses and also with the aid of literature data for authenticated samples.

Results: Cholesterol (1), baconipyrone D (2), chimyl alcohol (3), batyl alcohol (4), α-monpalmitin (5), stearic acid (6), 3-indolecarboxylic acid (7), uracil (8), thymine (9), uridine (10), thymidine (11) were isolated from the marine slug (Paraoncidium reevesii).

Conclusion: All the isolated compounds are being reported here for Paraoncidium reevesii for the first time. The results provide base data for further study of the Onchidiidae as a Chinese traditional remedy for asthma and athlete foot.

Keywords: Mollusk, Paraoncidium reevesii, Baconipyrone D, Batyl alcohol, Chimyl alcohol Onchidiidae, Marine Pulmonate, Slug, Asthma, Athlete foot